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Product Name | BGC 20-1531 (hydrochloride) |
Description | A potent and selective EP4 receptor antagonist (Kis = 11.7, >10,000, and >10,000 nM for EP4, EP2, and EP3, respectively); selective for EP4, exhibiting 2-induced cAMP accumulation in HEK293 EBNA cells that stably express human EP4 receptors; reverses PGE2-induced vasorelaxation (Kb = 15.85 nM) in human middle cerebral and middle meningeal arterial rings; prevents PGE2-induced increases in carotid blood flow and decreases in carotid resistance in dogs (ID50 = 5 mg/kg) |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | PGN 1531 |
Gene, Accession, CAS # | CAS: 1962928-26-2 |
Catalog # | 19742-10 |
Price | $335.00 |
Order / More Info | BGC 20-1531 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |