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Product Name | S26948 |
Description | A PPARγ agonist (EC50 = 8.83 nM in a transactivation assay); selective for PPARγ over PPARα, PPARβ/δ, and RXRα at 10 µM; decreases serum levels of glucose, triglycerides, non-esterified fatty acids, and insulin and increases hepatic palmitate oxidation in an ob/ob mouse model of type 2 diabetes at 30 mg/kg per day; decreases plasma levels of triglycerides and total and non-HDL cholesterol and the surface area of atherosclerotic lesions in the aortic sinus in an E2-KI transgenic mouse model of dyslipidemia and atherosclerosis fed a Western diet at 30 mg/kg |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | S-26948 PPAR-γ α β δ RXR nonesterified FA E2KI |
Gene, Accession, CAS # | CAS: 353280-43-0 |
Catalog # | 29722-5 |
Price | $140.00 |
Order / More Info | S26948 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |