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Product Name | MEDICA 16 |
Description | A GPR40 agonist and GPR120 partial agonist; induces intracellular calcium mobilization in cells expressing GPR40 or GPR120; induces ERK activation in cells expressing GPR40 or GPR120 at 100 µM; inhibits ATP citrate lyase (Kis = 40 and 200 µM for the oxidized and reduced enzyme, respectively); chronic dietary administration of MEDICA 16 (0.25% w/w) decreases liver ACC and AMPK levels in a model of insulin resistance using JCR:LA-cp rats; reduces plasma insulin levels, decreases fasting plasma triacylglycerol levels, and delays the onset of hyperinsulinemia in JCR:LA-cp rats at 0.25% w/w in the diet |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | hypolipidemic antidiabetogenic analogs fatty acids diabetes antidiabetic b,b'-hexadecanedioic nuclear receptors beta,beta-hexadecanedioic .beta.,.beta.'-hexadecanedioic VLDL decrease atherosclerosis |
Gene, Accession, CAS # | CAS: 87272-20-6 |
Catalog # | 90290-50 |
Price | $684.00 |
Order / More Info | MEDICA 16 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |