MEDICA 16 from CAYMAN CHEMICAL COMPANY

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Product NameMEDICA 16
DescriptionA GPR40 agonist and GPR120 partial agonist; induces intracellular calcium mobilization in cells expressing GPR40 or GPR120; induces ERK activation in cells expressing GPR40 or GPR120 at 100 µM; inhibits ATP citrate lyase (Kis = 40 and 200 µM for the oxidized and reduced enzyme, respectively); chronic dietary administration of MEDICA 16 (0.25% w/w) decreases liver ACC and AMPK levels in a model of insulin resistance using JCR:LA-cp rats; reduces plasma insulin levels, decreases fasting plasma triacylglycerol levels, and delays the onset of hyperinsulinemia in JCR:LA-cp rats at 0.25% w/w in the diet
Size50 mg
Concentrationn/a
Applicationsn/a
Other Nameshypolipidemic antidiabetogenic analogs fatty acids diabetes antidiabetic b,b'-hexadecanedioic nuclear receptors beta,beta-hexadecanedioic .beta.,.beta.'-hexadecanedioic VLDL decrease atherosclerosis
Gene, Accession, CAS #CAS: 87272-20-6
Catalog #90290-50
Price$684.00
Order / More InfoMEDICA 16 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
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