MC1742 from CAYMAN CHEMICAL COMPANY
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| Product Name | MC1742 |
| Description | An inhibitor of class I (IC50s = 0.1, 0.11, 0.02, 0.61 µM for HDAC1, -2, -3, and -8, respectively) and class IIb HDACs (IC50s = 7 and 40 nM for HDAC6 and HDAC10, respectively); selective for class I and class IIb over class IIa HDACs (IC50s = >50 µM for HDAC4, -5, -7, and -9); reduces proliferation of HOS, MG-63, RD, A204, SK-ES-1, and A673 sarcoma CSCs; increases levels of acetylated histone H3 and acetylated tubulin and induces apoptosis in MG-63 CSCs at 2 µM; reactivates HIV-1 in JLAT 10.6 latently-infected cells (EC50 = 350 nM) |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | MC 1742 HDAC 1 4 10 HDAC2 HDAC3 HDAC8 HDAC5 HDAC7 HDAC9 II b MG63 A 204 SKES1 A 673 H 3 HIV1 JLAT10.6 |
| Gene, Accession, CAS # | CAS: 1776116-74-5 |
| Catalog # | 29171-1 |
| Price | $153.00 |
| Order / More Info | MC1742 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY