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Product Name | Refametinib |
Description | An allosteric, selective inhibitor of MEK1 and MEK2 (IC50s = 19 and 47 nM, respectively); blocks phosphorylation of ERK1/2 across several human cancer cell lines differing in tissue origin and BRAF mutational status (EC50s = 2.5-16 nM); orally available and active in human tumor xenograft models |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ?RDEA119|BAY 86-9766 |
Gene, Accession, CAS # | CAS: 923032-37-5 |
Catalog # | 16997-5 |
Price | $111 |
Order / More Info | Refametinib from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |