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Product Name | NCT-02 |
Description | A degrader of cyclin K; the levels of cyclin K in patient-derived CRC cells in a concentration-dependent manner; inhibits cancer cell proliferation in CRC tissue samples isolated from the colon (IC50s = 0.9-20.6 µM), as well as from hepatic, lung, and rectal metastases (IC50s = 0.5-11.8, 1, and 1.4-38.4 µM, respectively); decreases the levels of ATM and RAD51 in patient-derived CRC tissues at 0.7 and 0.5 µM, respectively; reduces the number of spheroids formed and induces PARP cleavage in patient-derived CRC spheroid cultures at 3 µM |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | NCT02 RAD-51 ADPribose NCT2 -2 |
Gene, Accession, CAS # | CAS: 790245-61-3 |
Catalog # | 39568-10 |
Price | $232.00 |
Order / More Info | NCT-02 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |