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Product Name | Diazoxide |
Description | An activator of SUR1 linked to Kir6.2 (EC50 = 14.1 µM in a FLIPR assay using HEK293 cells); activates SUR2A/Kir6.2 and SUR2B/Kir6.2 channels in HEK293T cells in a patch-clamp assay at 30 and 300 µM; inhibits glucose-induced insulin release from isolated rat pancreatic β cells and induces relaxation of isolated rat aortic rings precontracted with potassium chloride (IC50s = 22.6 and 22.4 µM, respectively); reduces mean arterial pressure and cerebral blood flow in spontaneously hypertensive rats at an intravenous 5 mg/kg bolus dose; increases blood glucose levels in mice at 50 mg/kg i.p. |
Size | 100 mg |
Concentration | n/a |
Applications | n/a |
Other Names | NSC 64198|NSC 76130|SRG 95213 |
Gene, Accession, CAS # | CAS: 364-98-7 |
Catalog # | 14576-100 |
Price | $63.00 |
Order / More Info | Diazoxide from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |