Roflumilast from CAYMAN CHEMICAL COMPANY
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| Product Name | Roflumilast |
| Description | A PDE4 inhibitor (IC50 = 0.8 nM); selective for PDE4 over PDE1, -2, -3, and -5 (IC50s = >10, >10, >10, and 8 µM, respectively); inhibits fMLP-induced LTB4 production in isolated human neutrophils (IC50 = 2 nM); reduces the proliferation of anti-CD3 and anti-CD28-stimulated isolated human CD4+ T cells (IC30 = 7 nM); prevents pulmonary inflammatory cell infiltration and emphysema in mice exposed to cigarette smoke at 5 mg/kg |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | B 9302-107|BY 217|BYK 20869 |
| Gene, Accession, CAS # | CAS: 162401-32-3 |
| Catalog # | 15141-25 |
| Price | $219 |
| Order / More Info | Roflumilast from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY