X-82 from CAYMAN CHEMICAL COMPANY
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| Product Name | X-82 |
| Description | A multi-kinase inhibitor; inhibits VEGFR2, PDGFRβ, FLT3, and c-Kit (IC50s = 1.12, 0.13, 0.63, and 0.14 nM, respectively) and is selective for these kinases over RET and AMPKα1 (IC50s = 74.1 and 352.2 nM, respectively); inhibits VEGF-induced proliferation of HUVECs (IC50 = 31 nM); decreases VEGF-induced capillary tube formation in HUVECs at 1 µM; reduces FBS-induced migration of HUVECs at 0.01 or 0.1 µM; reduces tumor volume and growth alone and in combination with gefitinib in an HCC827 NSCLC mouse xenograft model at 80 mg/kg per day |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | CM082|Vorolanib |
| Gene, Accession, CAS # | CAS: 1013920-15-4 |
| Catalog # | 38765-1 |
| Price | $79.00 |
| Order / More Info | X-82 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY