MRTX-0902 from CAYMAN CHEMICAL COMPANY
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| Product Name | MRTX-0902 |
| Description | An inhibitor of the SOS1-K-RasG12C protein-protein interaction (Ki = 1.9 nM); selective for the SOS1-K-RasG12C protein-protein interaction over the SOS1-K-Ras protein-protein interaction (IC50 = >10,000 nM); decreases phosphorylated ERK levels in MNK1 cancer cells (IC50 = 29 nM); reduces tumor volume and phosphorylated ERK levels when combined with MTX-849 in a PaCa-2 pancreatic cancer mouse xenograft model at 25 or 50 mg/kg twice per day |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | SOS1KRasG12C SOS1 KRasG12C SOS 1 KRas MTX849 PaCa2 MRTX0902 MRTX902 902 |
| Gene, Accession, CAS # | CAS: 2654743-22-1 |
| Catalog # | 38578-1 |
| Price | $75.00 |
| Order / More Info | MRTX-0902 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY