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Product Name | Resolvin E4 |
Description | An SPM; produced from EPA by 15-LO via 15(S)-HpEPE and 15S-hydroxy, 5S-HpEPE intermediates in vitro and by isolated human M2 macrophages or PMN neutrophils under normoxic or hypoxic conditions; enhanced synthesis in M2 macrophage and neutrophil co-cultures, indicating transcellular biosynthesis by a potential 15-LO and 5-LO mechanism; has been found in mouse inflammatory exudates; increases efferocytosis of apoptotic neutrophils or sRBCs by human M2 macrophages under hypoxic conditions in vitro; inhibits zymosan A- and thrombin-induced increases in inflammatory exudate neutrophil infiltration in a mouse model of hemorrhagic peritonitis at 100 ng/animal; increases inflammatory exudate macrophage infiltration and efferocytosis of apoptotic neutrophils and/or RBCs in the same model |
Size | 10 µg |
Concentration | n/a |
Applications | n/a |
Other Names | RvE4 |
Gene, Accession, CAS # | CAS: 1781227-87-9 |
Catalog # | 29590-10 |
Price | $121 |
Order / More Info | Resolvin E4 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |