Edit |   |
---|---|
Product Name | Cyclizine (hydrochloride) |
Description | A histamine H1 receptor antagonist; binds selectively to histamine H1 receptors (Kd = 5 nM) over H2 and H3 receptors (Kds = 1,600 and >580 nM, respectively); inhibits anti-IgE-induced histamine release from isolated human lung fragments (IC50 = 5.42 µM) but also induces histamine release (RC50 = 10.81 µM); reduces LPS-induced nitrite accumulation and protein levels of iNOS in RAW 264.7 cells at 100 nM; reduces immobility in the forced swim test in rats at 10 and 20 mg/kg |
Size | 5 g |
Concentration | n/a |
Applications | n/a |
Other Names | 82-92-8 H 1 2 3 |
Gene, Accession, CAS # | CAS: 303-25-3 |
Catalog # | 31190-5 |
Price | $704.00 |
Order / More Info | Cyclizine (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |