NCI 126224 from CAYMAN CHEMICAL COMPANY
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| Product Name | NCI 126224 |
| Description | A TLR4 antagonist; selectively inhibits NO production induced by LPS (IC50 = 0.31 µM) over the R-848, Pam3CSK4, and poly(I:C) in RAW 264.7 macrophages but also inhibits NO production induced by FSL-1 in the same cells at 0.6 µM; inhibits LPS-induced NF-κB activity in a reporter assay using BV-2 microglial cells and LPS-induced increases in IL-1β and TNF-α levels in RAW 264.7 macrophages (IC50s = 5.92, 0.42, and 1.54 µM, respectively) |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | NSC 126224 |
| Gene, Accession, CAS # | CAS: 65974-52-9 |
| Catalog # | 39520-25 |
| Price | $447.00 |
| Order / More Info | NCI 126224 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
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http://www.caymanchem.com
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