MK-4101 from CAYMAN CHEMICAL COMPANY
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| Product Name | MK-4101 |
| Description | A Smoothened receptor antagonist; binds to human recombinant Smo expressed in HEK293T cells (IC50 = 1.1 µM); inhibits Gli1-mediated hedgehog signaling in a reporter assay (IC50 = 1.5 µM); an inhibitor of 11β-hydroxy steroid dehydrogenase-1; reduces tumor growth in a murine medulloblastoma mouse allograft model at 40 and 80 mg/kg per day); induces tumor regression at 80 mg/kg twice per day; reduces expression of the hedgehog pathway-associated transcription factor Gli1 in tumor tissue |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | MK4101 HEK 293T 293 T Gli 1 11 β |
| Gene, Accession, CAS # | CAS: 935273-79-3 |
| Catalog # | 29159-25 |
| Price | $704.00 |
| Order / More Info | MK-4101 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY