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Product Name | Cabazitaxel |
Description | A semisynthetic taxane; stabilizes microtubule assembly by reducing lag time for tubulin assembly (LT50 = 100 nM) and the rate of cold-induced microtubule depolymerization (IC50 = 100-250 nM) in vitro; inhibits proliferation of P388, HL-60, Calc18, and KB cells (IC50s = 4-41 nM), as well as P-glycoprotein-expressing, drug-resistant versions of these cell lines (IC50s = 16-414 nM); dose-dependently reduces tumor growth in docetaxel-susceptible N87 human gastric carcinoma and docetaxel-resistant UISO BCA-1 breast cancer mouse xenograft models, |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | TXD 258|XRP 6258 |
Gene, Accession, CAS # | CAS: 183133-96-2 |
Catalog # | 22262-50 |
Price | $257.00 |
Order / More Info | Cabazitaxel from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |