RVX-208 from CAYMAN CHEMICAL COMPANY
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| Product Name | RVX-208 |
| Description | A selective antagonist of BET bromodomains, binding with 10-100-fold higher affinity for BD2 (IC50 = 0.04-0.28 µM) over BD1 (IC50 = 1.8-3.1 µM), which causes selective release of BET proteins from chromatin; increases the expression of ApoA1 and reduces atherosclerosis in hyperlipidemic ApoE-deficient mice |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | epigenetics atherosclerosis proteins bindings chromatins research BD1 BD2 BDs 1 2 ones twos BD-1 BD-2 RVXs RVX208 208 bromodomains selective antagonists BETs cells apolipoproteins ApoA1 A1 mice mouse monkeys humans hyperlipidemic ApoE deficient deficiency deficiencies 1246400-89-4 1431550-07-0 RVX 000222 biochemicals |
| Gene, Accession, CAS # | CAS: 1044870-39-4 |
| Catalog # | 16424-1 |
| Price | $44.00 |
| Order / More Info | RVX-208 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY