Norquetiapine from CAYMAN CHEMICAL COMPANY
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| Product Name | Norquetiapine |
| Description | An active metabolite of quetiapine; selectively inhibits NET (IC50 = 12 nM) over SERT and DAT (IC50s = 988 and >10,000 nM, respectively); binds to the histamine H1 receptor (Ki = 3.5 nM), as well as 5-HT1, 5-HT2, and 5-HT7, α1- and α2-adrenergic, dopamine D1-D5, and M1-M5 muscarinic receptors (Kis = 45-1,117 nM, 95-736, 196-1,419, and 23-453 nM, respectively); an antagonist at histamine H1, α1A- and α1D-adrenergic, M1, M3, and M5 muscarinic receptors in a concentration-dependent manner and an agonist at the 5-HT1A receptor (EC50 = 4,898 nM); reduces increases in immobility time in Vmat2 heterozygous mice at 0.1, 0.5, and 1 mg/kg |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | N-Desalkylquetiapine |
| Gene, Accession, CAS # | CAS: 5747-48-8 |
| Catalog # | 36687-25 |
| Price | $183.00 |
| Order / More Info | Norquetiapine from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY