CP 376,395 from CAYMAN CHEMICAL COMPANY
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| Product Name | CP 376,395 |
| Description | A CRF1 antagonist (IC50 = 5.1 nM); inhibits adenylate cyclase activity stimulated by ovine CRF in rat cerebral cortex and at human CRF1 receptors; inhibits CRF-induced increases in the acoustic startle response in rats at 17.8 mg/kg; increases the percentage of open arm entries and time spent in the open arms of the elevated plus maze in mice at 1.5 and 3 nmol; reduces ethanol consumption in rats trained on an intermittent access schedule at 10 mg/kg; increases pulmonary ventilation in rats under normocapnic and hypercapnic conditions at 5 nmol/0.1 µl |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | CP 316,311 |
| Gene, Accession, CAS # | CAS: 175140-00-8 |
| Catalog # | 29188-1 |
| Price | $116.00 |
| Order / More Info | CP 376,395 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
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