TBPB from CAYMAN CHEMICAL COMPANY

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Product NameTBPB
DescriptionAn allosteric agonist of M1 mAChRs (EC50 = 158 nM in CHO-K1 cells expressing rat recombinant receptors); selective for M1 over M2-5 receptors at concentrations up to 10 µM; potentiates NMDA-evoked currents in CA1 pyramidal cells at 3 µM; increases production of the non-amyloidogenic APP cleavage products APPsα and CTFα in PC12 cells overexpressing the human M1 receptor and APP at 1 µM; decreases amphetamine-induced hyperlocomotion in in a rat model that is predictive of antipsychotic-like activity
Size10 mg
Concentrationn/a
Applicationsn/a
Other Namesmuscarinic M-1 agonist tert-butyl peroxybenzoate M2 M3 M4 M5 2 3 4 5 CA Sα CTF-α PC-12 over-expressing hyper-locomotion anti-psychotic nonamyloidogenic
Gene, Accession, CAS #CAS: 634616-95-8
Catalog #22943-10
Price$163.00
Order / More InfoTBPB from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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