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Product Name | TBPB |
Description | An allosteric agonist of M1 mAChRs (EC50 = 158 nM in CHO-K1 cells expressing rat recombinant receptors); selective for M1 over M2-5 receptors at concentrations up to 10 µM; potentiates NMDA-evoked currents in CA1 pyramidal cells at 3 µM; increases production of the non-amyloidogenic APP cleavage products APPsα and CTFα in PC12 cells overexpressing the human M1 receptor and APP at 1 µM; decreases amphetamine-induced hyperlocomotion in in a rat model that is predictive of antipsychotic-like activity |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | muscarinic M-1 agonist tert-butyl peroxybenzoate M2 M3 M4 M5 2 3 4 5 CA Sα CTF-α PC-12 over-expressing hyper-locomotion anti-psychotic nonamyloidogenic |
Gene, Accession, CAS # | CAS: 634616-95-8 |
Catalog # | 22943-10 |
Price | $163.00 |
Order / More Info | TBPB from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |