AA147 from CAYMAN CHEMICAL COMPANY
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| Product Name | AA147 |
| Description | An ER proteostasis regulator; activates an ATF6-dependent ER stress response element reporter and antioxidant response element reporter in HT22 hippocampal cells (EC50s = 3.6 and 3.92 µM, respectively) and protects against glutamate-induced cytotoxicity and prevents increases in ROS in HT22 cells at 10 µM; reduces tunicamycin-induced cell death and increases ERAD in neonatal rat ventricular myocytes at 10 µM; reduces the myocardial, renal, and cerebral infarct size as a percentage of the area at risk in mouse models of ischemia-reperfusion injury induced by LAD ligation, renal portal system occlusion, or MCAO, respectively at 2 mg/kg; prevents the production of NS5 in dengue virus-infected Huh7 cells (IC50 = ~1 µM) |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | AA-147 ATF-6 anti-oxidant HT-22NS-5 Huh-7 |
| Gene, Accession, CAS # | CAS: 393121-74-9 |
| Catalog # | 27143-5 |
| Price | $26.00 |
| Order / More Info | AA147 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY