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Product Name | MRS2179 (ammonium salt hydrate) |
Description | A competitive purinergic P2Y1 receptor antagonist (Kb = 102 nM); selective for P2Y1 over P2Y2, P2Y4, P2Y6, P2Y12, and P2Y13, as well as P2X1-4, receptors at 10 µM; reduces 2-MeSADP-induced PLC activity (IC50 = 331 nM in turkey erythrocyte membranes); inhibits ADP-induced platelet shape change and aggregation in washed isolated human platelets at 10 µM; prolongs the length of tail bleeding time in mice, as well as decreases platelet thrombus formation in a mouse model of iron chloride-induced arterial thrombosis at 50 mg/kg |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | platelet aggregation P2Y1 P2Y-1 MRS-2179 2'-deoxy-N6-methyladenosine 3',5'-bisphosphate 101204-49-3 228264-19-5 |
Gene, Accession, CAS # | n/a |
Catalog # | 10011450-5 |
Price | $129.00 |
Order / More Info | MRS2179 (ammonium salt hydrate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |