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Product Name | Zonisamide |
Description | A broad-spectrum sulfonamide antiepileptic agent; blocks repeated firing of Na+ (IC50 = 2 µg/ml) and T-type Ca2+ channels; inhibits recombinant H. pylori CA and human CAI, CAII, and CAV (Kis = of 218, 56, 35, and 21 nM, respectively); has anticonvulsant activity in MES models in rats, rabbits, dogs, and mice with a potency similar to phenobarbital and carbamazepine; acts as an anticonvulsant against MES and pentylenetetrazole-induced maximal and minimal seizures in mice (median effective doses = 19.6, 9.3, and >500 mg/kg, p.o., respectively); dose-dependently prevents reduction of dopamine, HVA, and DOPAC levels and the elevation of the dopamine turnover rate induced by MPTP in mice |
Size | 250 mg |
Concentration | n/a |
Applications | n/a |
Other Names | CI-912|PD 110843 |
Gene, Accession, CAS # | CAS: 68291-97-4 |
Catalog # | 24183-250 |
Price | $118.00 |
Order / More Info | Zonisamide from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |