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Product Name | N-(n-Butyl)deoxygalactonojirimycin |
Description | An inhibitor of glucosylceramide synthase, GBA, GBA2, acid α-glucosidase, sucrase, maltase, and lactase; reduces glycolipid levels in HL-60 and WEHI-3B cells from 0.5-500 µM; decreases brain ganglioside levels in a Glb1-/-neonatal mouse model of GM1 gangliosidosis at 600 and 1,200 mg/kg four times per day for three days; increases testicular glucosylceramide levels in mice from 1-1,200 mg/kg per day for 35 days; induces abnormal spermatid and acrosome formation, as well as reduces motility, in isolated mouse epididymal sperm at 15, 25, and 50 mg/kg per day; induces infertility, an effect that is reversed by withdrawal, in the same model |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Lucerastat|NBDGJ |
Gene, Accession, CAS # | CAS: 141206-42-0 |
Catalog # | 19520-5 |
Price | $193.00 |
Order / More Info | N-(n-Butyl)deoxygalactonojirimycin from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |