Edit |   |
---|---|
Product Name | MI 2 |
Description | A MALT1 inhibitor (IC50 = 5.84 µM in a fluorescence assay); inhibits the growth of MALT1-dependent ABC-DLBCL cell lines (GI50s = 0.2, 0.5, 0.4, and 0.4 µM for HBL-1, TMD8, OCI-Ly3, and OCI-Ly10 cells, respectively); inhibits cleavage of the MALT1 target protein CYLD in a dose-dependent manner in HBL-1 cells; reduces tumor size in TMD8 and HBL-1 mouse xenograft models when administered at a dose of 25 mg/kg, i.v. |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | MI2 MALT-1 Mucosa-associated lymphoid tissue translocation protein ABCDLBCL HBL1 TMD-8 OCILy3 OCILy10 |
Gene, Accession, CAS # | CAS: 1047953-91-2 |
Catalog # | 23437-1 |
Price | $32.00 |
Order / More Info | MI 2 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |