ML-290 from CAYMAN CHEMICAL COMPANY
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| Product Name | ML-290 |
| Description | An RXFP1 agonist (EC50 = 0.094 µM for the human receptor in a cAMP production assay); selective for RXFP1 over RXFP2 (EC50 = 1.5 µM); induces expression of VEGF in THP-1 cells expressing human RXFP1 at 250 nM; stimulates cAMP release from HEK293 cells expressing the human, macaque, pig, or rabbit receptors, but not the guinea pig or mouse receptors; increases the expression of MMP1 and PPARGC1A and decreases COL1A1 expression in primary human hepatic stellate cells at 5 µM; reduces carbon tetrachloride-induced liver fibrosis in transgenic mice expressing human RXFP1 at 37 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | RXFP1 Agonist 8?? |
| Gene, Accession, CAS # | CAS: 1482500-76-4 |
| Catalog # | 21134-5 |
| Price | $120.00 |
| Order / More Info | ML-290 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY