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Product Name | Treprostinil |
Description | Treprostinil is a stable analog of prostacyclin (Item No. 18220) that is used clinically for the treatment of PPH under the trade name Remodulin™. The structural modifications in treprostinil compared to prostacyclin increase the plasma half-life from 2 minutes to 34 and 85 minutes for intravenous and subcutaneous infusion of the drug, respectively.{13285} In addition to treprostinil's direct vasodilatory effects, it also inhibits inflammatory cytokine (TNFα, IL-1β, IL-6, GM-CF) production by human alveolar macrophages in the sub-micromolar range by preventing NF-κB translocation to the nucleus.{12665} |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | BW 15AU|LRX 15|Rumodolin|U-62840|Uniprost |
Gene, Accession, CAS # | CAS: 81846-19-7 |
Catalog # | 10162-1 |
Price | $97.00 |
Order / More Info | Treprostinil from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |