VTX-27 from CAYMAN CHEMICAL COMPANY

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Product NameVTX-27
DescriptionA PKCθ inhibitor (Ki = 0.08 nM); selective for PKCθ over PKCα, -βI, -βII, -γ, -δ, -ε, -η, -μ, and -ζ (Kis = 1->5,000 nM) as well as a panel of seven kinases from the Src, Syk, Tec, and MAP kinase families (Kis = >1,000 nM for all); inhibits CD28-induced IL-2 release in isolated human PBMCs (IC50 = 11 nM); prevents staphylococcal enterotoxin B-induced increases in IL-2 plasma levels in mice at 12.5, 25, and 50 mg/kg, p.o.
Size1 mg
Concentrationn/a
Applicationsn/a
Other NamesVTX27 PKC θ PKC α cd 28 IL2 peripheral blood mononuclear cell
Gene, Accession, CAS #CAS: 1321924-70-2
Catalog #36938-1
Price$183.00
Order / More InfoVTX-27 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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