Pinaverium (bromide) from CAYMAN CHEMICAL COMPANY
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| Product Name | Pinaverium (bromide) |
| Description | An L-type calcium channel inhibitor (IC50 = 1.5 µM in a patch-clamp assay using isolated rabbit jejunal smooth muscle cells); binds to CHO cells expressing the Cav1.2 α1C-a or α1C-b subunits (Kis = 1.5 and 2.92 µM, respectively); inhibits ACh- or potassium chloride-induced contractions in colonic circular muscle strips isolated from non-stressed or cold-restraint-stressed rats (IC50s = 0.91 and 1.66 µM for ACh, respectively, and 3.8 and 8.13 µM for potassium chloride, respectively) in a model of stress-induced smooth muscle contractility disorder; increases survival and decreases pulmonary neutrophil infiltration in a mouse model of LPS-induced septic shock from 1-10 mg/kg |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | PVB |
| Gene, Accession, CAS # | CAS: 53251-94-8 |
| Catalog # | 40653-25 |
| Price | $344.00 |
| Order / More Info | Pinaverium (bromide) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY