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Product Name | CPYPP |
Description | An inhibitor of DOCK2 (IC50 = 22.8 µM for its GEF activity), DOCK5, and DOCK180; selective for these DOCKs over DOCK9; prevents chemokine-induced Rac activation in T and B cells at 100 µM; reduces migration of T cells to peripheral lymph nodes in mice at 5 mg/animal following adoptive transfer of spleen cells from knock-in mice expressing GFP-tagged DOCK2; reduces MPO activity in lung tissue, LPS-induced cytokine release in serum, and lung injury severity in a mouse model of endotoxemia-induced acute lung injury at 250 mg/kg |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1413941-71-5 1413941-83-9 1426543-36-3 DOCK-2 5 9 180 DOCKA DOCKD Lipopolysaccharide |
Gene, Accession, CAS # | CAS: 310460-39-0 |
Catalog # | 17386-5 |
Price | $68.00 |
Order / More Info | CPYPP from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |