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Product Name | BI-605906 |
Description | An IKKβ inhibitor (IC50 = 380 nM); selective for IKKβ over insulin-like growth factor 1 (IGF1; IC50 = 7.6 µM) and over 100 kinases in a panel up to 10 µM; partially inhibits IL-1-stimulated activation of IKKε/TBK1 in vitro; inhibits TNF-α-dependent IkB degradation and expression of the proinflammatory cytokines IL-6, IL-1β, and CXCL1/2 without affecting lipogenic gene expression or glucose production in murine primary hepatocytes, |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | BI605906 IKB IL6 IL1β CXCL1/2 CXCL-1 2 CXC TBK |
Gene, Accession, CAS # | CAS: 960293-88-3 |
Catalog # | 19184-10 |
Price | $317.00 |
Order / More Info | BI-605906 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |