CC-671 from CAYMAN CHEMICAL COMPANY
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| Product Name | CC-671 |
| Description | A dual inhibitor of Mps1/TTK and Clk2 (IC50s = 5 and 3 nM, respectively); selective for Mps1/TTK and Clk2 over a panel of 255 kinases at 3 µM; inhibit DYRK3, DYRK1A, PHKG, DYRK1B, and Clk1 (IC50s = 99, 104, 136, 157, and 300 nM, respectively); selectively inhibits the growth of Cal-51 TNBC cell over BT-474 luminal breast cancer cells (IC50s = 60 and 6,970 nM, respectively); reduces tumor volume in a Cal-51 mouse xenograft model at 20 mg/kg |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | CC671 CLK-2 1 CDC-2 Mps-1 DYRK-3 1A 1B Cal51 BT474 |
| Gene, Accession, CAS # | CAS: 1618658-88-0 |
| Catalog # | 26184-10 |
| Price | $243.00 |
| Order / More Info | CC-671 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY