1A-116 from CAYMAN CHEMICAL COMPANY

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Product Name1A-116
DescriptionAn inhibitor of Rac1 (IC50 = 4 µM); reduces the secretion of CXCL5, CXCL10, HGF, CCL2, and MMP-2 from patient-derived AML cells at 20 µM; inhibits the proliferation and migration of, and induces apoptosis in, LN-229 glioblastoma cells at 10 hours, but not 23 hours, post-synchronization at 20 µM; decreases the number of lung nodules and macronodules, as well as total lung weight, in a F3II murine breast cancer model of lung tumor formation at 3 mg/kg per day; inhibits the asexual replication of the P. falciparum strains D10 and W2 (IC50s = 3.21 and 6.89 µM, respectively) and sexual replication in P. falciparum 3D7 immature and mature gametocytes (IC50s = 78.13 and 56.64 µM, respectively)
Size50 mg
Concentrationn/a
Applicationsn/a
Other Names1A116 Rac-1 CXCL CCL MMP2 LN229 Plasmodium D-10
Gene, Accession, CAS #CAS: 1430208-73-3
Catalog #40781-50
Price$177.00
Order / More Info1A-116 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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