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Product Name | CPI-455 |
Description | A KDM5 inhibitor; selectively inhibits KDM5A-D (IC50s = 2-10 nM) over KDM2-4, 6, and 7 family members (IC50s = 1 to >25 µM); increases histone H3K4me2/3 methylation in vitro; decreases the number of drug-tolerant cancer cells in PC9, M14, and SKBR3 cell populations; reduces growth of TMZ-resistant glioblastoma cells in a dose-dependent manner, |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1628332-43-3 CPI455 KDM5 H3K4 M-14 PC-9 SKBR-3 |
Gene, Accession, CAS # | CAS: 1628208-23-0 |
Catalog # | 22127-1 |
Price | $26.00 |
Order / More Info | CPI-455 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |