LY294002 (hydrochloride) from CAYMAN CHEMICAL COMPANY
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| Product Name | LY294002 (hydrochloride) |
| Description | A multi-kinase inhibitor; inhibits CK2 (IC50 = 0.098 µM), the PI3K subunits p110α, p110β, p110δ, and p110γ (IC50s = 0.497, 0.554, 0.331, and 3.8 µM, respectively), and DNA-PK (IC50 = 6 µM), among other kinases, as well as CK1, GSK3α, and GSK3β by greater than 40% at 10 µM; reduces viability of SGC-7901 cells at 12.5, 25, and 50 µM; induces apoptosis and autophagy in SGC-7901 cells at 50 µM; reduces tumor volume in DLD-1 and LoVo mouse xenograft models at 2 ng/ml/kg; reduces aging-induced increases in the number of aging SA-β-gal-positive human VSMCs at 20 µM in the 5th to 15th generations |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 154447-36-6 LY-294002 multikinase CK PI3-K p110-α β δ γ DNAPK GSK-3α 3β SGC7901 DLD1 βgalactosidase SAβgal βgal SAβ |
| Gene, Accession, CAS # | CAS: 934389-88-5 |
| Catalog # | 39171-25 |
| Price | $250.00 |
| Order / More Info | LY294002 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY