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Product Name | Nuciferine |
Description | An alkaloid with diverse biological activities; partial agonist at dopamine D2 receptors, as well as an inverse agonist at the serotonin receptor subtype 5-HT7, and an antagonist at the 5-HT2B and 5-HT2C receptors (EC50s = 65.07, 150, 478, and 131 nM, respectively); an antagonist at schistosome Sm.5-HTRL receptors (IC50 = 240 nM); inhibits 5-HT-induced motility of larval and adult S. mansoni at 10 µM; activates PPARα, PPARβ/δ, and PPARγ transcriptional activity; prevents RSL3-induced ferroptotic cell death in HK-2 and HEK293T cells at 10, 20, and 40 µM; reduces serum hyperlipidemia and hepatic steatosis in a mouse model of high-fat diet-induced hyperlipidemia |
Size | 100 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (-)-Nuciferine|Sanjoinine E|VLT 049 |
Gene, Accession, CAS # | CAS: 475-83-2 |
Catalog # | 33839-100 |
Price | $553.00 |
Order / More Info | Nuciferine from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |