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Product Name | NMS-P715 |
Description | An Mps1/TTK inhibitor (IC50 = 0.182 µM); selective for Mps1/TTK over a panel of 59 additional kinases (IC50s = >5 µM for all); accelerates mitosis, reducing the length of mitosis by approximately 3-fold, in U2OS cells; induces aneuploidy and apoptosis in A2780 ovarian cancer cells at 1 µM, as well as inhibits proliferation in a panel of 127 cancer cell lines (IC50s = 0.192-10 µM); reduces tumor growth in an A2780 mouse xenograft model at 90 mg/kg per day |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | NMSP715 Mps 1 A 2780 |
Gene, Accession, CAS # | CAS: 1202055-32-0 |
Catalog # | 31613-25 |
Price | $830.00 |
Order / More Info | NMS-P715 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |