Echinocystic Acid from CAYMAN CHEMICAL COMPANY
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| Product Name | Echinocystic Acid |
| Description | A triterpene with diverse biological activities; induces nuclear translocation of the GR and reduces TNF-α-induced NF-κB signaling in HEK293 cells overexpressing GFP-GR; suppresses RANKL-induced NF-κB activation, ERK phosphorylation, and osteoclastogenesis in mouse BMMs at 12.5, 25, and 50 µM; induces neurite outgrowth in Neuro2A cells; decreases escape latency in the Morris water maze and increases the length of neurite processes in the hippocampus of aged mice at 10 mg/kg per day; topical administration reduces TPA-induced expression of COX-2, iNOS, TNF-α, and IL-1β and ear edema in a mouse model of dermatitis; recovers reductions in femoral bone mineral density and trabecular thickness and number in a rat model of ovariectomy-induced osteoporosis |
| Size | 50 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 17020-07-4 Gleditsia TNFα NFκB HEK 293 GFPGR Neuro 2A SP600125 COX2 IL1β BMM NOS Echino-cystic |
| Gene, Accession, CAS # | CAS: 510-30-5 |
| Catalog # | 27476-50 |
| Price | $467.00 |
| Order / More Info | Echinocystic Acid from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY