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Product Name | 1-Oleoyl Lysophosphatidic Acid |
Description | 1-Oleoyl LPA is a species of LPA containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of PLD or through a two step process involving liberation of DAG by PLC followed by phosphorylation of DAG by diglycerol kinase.{2656} Hydrolysis of the fatty acid at the sn-2 position by PLA2 yields bioactive LPA. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{13001,2656} 1-Oleoyl LPA is the most potent of the LPA analogs for calcium mobilization in A431 cells and for growth stimulation of a variety of cell lines.{2665,2666} |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1-Oleoyl LPA|Oleoyl-sn-3-Glycerophosphate |
Gene, Accession, CAS # | CAS: 65528-98-5 |
Catalog # | 10010093-5 |
Price | $102.00 |
Order / More Info | 1-Oleoyl Lysophosphatidic Acid from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |