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Product Name | ASLAN003 |
Description | A DHODH inhibitor (IC50 = 35 nM); inhibits proliferation of MOLM-14 and KG-1 AML cells (IC50s = 0.582 and 0.382 µM, respectively) and induces apoptosis in the same cells at 0.5 and 1 µM; induces differentiation in bone marrow cells isolated from patients with AML or MDS at 1, 2, and 4 µM; improves survival in a PDX mouse model of AML at 50 mg/kg |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2170642-90-5 ASLAN 003 MOLM14 KG1 |
Gene, Accession, CAS # | CAS: 1035688-66-4 |
Catalog # | 33516-25 |
Price | $172.00 |
Order / More Info | ASLAN003 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |