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Product Name | Nav1.7 Blocker 52 |
Description | An inhibitor of Nav1.7 (IC50 = 0.17 µM); selective for Nav1.7 over hERG/Kv11.1, Nav1.5, and Nav1.8 (IC50s = >10, 1.1, and 2.2 µM, respectively) but does inhibit Nav1.3 and Nav1.4 (IC50s = 0.3 and 0.4 µM, respectively); inhibits formalin-induced flinching in a rat model of persistent pain at 20 and 30 mg/kg; increases latency to paw withdrawal in a hot plate test in a mouse model of CFA-induced inflammatory pain |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | TC-N 1752|Voltage-gated Sodium Channel 1.7 |
Gene, Accession, CAS # | CAS: 1211866-85-1 |
Catalog # | 34477-50 |
Price | $1,024.00 |
Order / More Info | Nav1.7 Blocker 52 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |