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Product Name | AS-19 |
Description | A 5-HT7 receptor agonist (IC50 = 0.83 nM); selective for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Kis = 89.7, 490, 6.6 and 98.5 nM, respectively), as well as sigma-1 and imidazoline I2 receptors (Kis = 657 and 282 nM, respectively); increases conditioned responses and reverses scopolamine-induced amnesia in rats in an autoshaping learning task at 5 mg/kg administered post-training; increases the paw withdrawal threshold in a mechanical pressure test in rats with chronic constriction injury when 0.3 µl of a 1.5 nM solution is injected into the vlPAG |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | AS19 5HT7 HT 7 1A 1B 1D 5A 5HT 5HT1A 5HT1B 5HT1D 5HT5A sigma1 I 2 SB269970 |
Gene, Accession, CAS # | CAS: 1000578-26-6 |
Catalog # | 20642-10 |
Price | $249.00 |
Order / More Info | AS-19 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |