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Product Name | Teneligliptin (hydrobromide hydrate) |
Description | A DPP-4 inhibitor (IC50s = 0.37 and 0.29 nM for the human and rat enzymes, respectively); selective for DPP-4 over DPP-8 and DPP-9 (IC50s = 260 and 540 nM, respectively, for the human enzymes); inhibits increases in plasma glucose levels in an oral glucose tolerance test in Zucker fatty rats at 0.03-1 mg/kg; reduces body weight, inhibits hepatic steatosis, and decreases plasma insulin levels in a mouse model of high-fat diet-induced obesity at 30 and 60 mg/kg; scavenges hydroxyl radicals in a cell-free assay (IC50 = 0.315 mM); decreases urinary levels of 8-OHdG in a DPP-4-deficient rat model of STZ-induced diabetes at 10 mg/kg per day |
Size | 250 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 760937-92-6 906093-29-6 DPP4 DPP8 DPP9 8OHdG |
Gene, Accession, CAS # | CAS: 1572583-29-9 |
Catalog # | 29515-250 |
Price | $139.00 |
Order / More Info | Teneligliptin (hydrobromide hydrate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |