Edoxaban (tosylate) from CAYMAN CHEMICAL COMPANY
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| Product Name | Edoxaban (tosylate) |
| Description | An orally bioavailable and potent inhibitor of factor Xa (Kis = 0.561 and 0.903 nM for free and complexed human factor Xa, respectively); >10,000-fold selective for factor Xa over thrombin, FVIIa/sTF, FXIa, tPA, aPC, trypsin, plasmin, and chymotrypsin; prolongs prothrombin, activated partial thromboplastin, and thrombin clotting times in a concentration-dependent manner ex vivo in human plasma; reduces thrombus formation and prolongs prothrombin time in a dose-dependent manner in rat and rabbit models of venous stasis thrombosis when administered at doses ranging from 0.5-12.5 mg/kg; reduces thrombus formation in a rat model of platinum wire-induced venous thrombosis |
| Size | 500 µg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | DU-176b |
| Gene, Accession, CAS # | CAS: 480449-71-6 |
| Catalog # | 24030-500 |
| Price | $33.00 |
| Order / More Info | Edoxaban (tosylate) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY