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Product Name | Lys05 (hydrochloride) |
Description | An inhibitor of autophagy; induces p62 accumulation and increases the ratio of LC3-II to LC3-I in C8161 melanoma cells in a concentration-dependent manner; increases the number of autophagic vesicles per cell in tumors in a C8161 mouse xenograft model and reduces tumor volume and growth in a 1205Lu melanoma mouse xenograft model at 76 mg/kg; reduces tumor growth rate, volume, and weight in an HT-29 colon cancer mouse xenograft model at ≥10 mg/kg but increases bowel thickness and obstruction at 80 mg/kg |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Lys01 |
Gene, Accession, CAS # | CAS: 1391426-24-6 |
Catalog # | 27334-50 |
Price | $360.00 |
Order / More Info | Lys05 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |