KHS-101 from CAYMAN CHEMICAL COMPANY

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Product NameKHS-101
DescriptionAn Hsp60 inhibitor and inducer of neuronal differentiation; inhibits the refolding activity of the complex of Hsp60 with the co-chaperone Hsp10 in a cell-free assay (IC50 = 14.4 µM); induces differentiation of primary rat hippocampal NPCs into neurons (EC50 = ~1 µM) and inhibits BMP4-induced differentiation of primary rat hippocampal NPCs into astrocytes at 5 µM; increases nuclear localization of the Tacc3 target Arnt2 in HEK293T cells expressing the rat proteins at 5 µM; reduces tumor burden and increases survival in a PDX mouse model of giant cell glioblastoma
Size50 mg
Concentrationn/a
Applicationsn/a
Other NamesKHS101 Arnt BMP-4 GBM Hsp HSPD HEK-293T 293 Tacc
Gene, Accession, CAS #CAS: 1262770-73-9
Catalog #37544-50
Price$507.00
Order / More InfoKHS-101 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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