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Product Name | KHS-101 |
Description | An Hsp60 inhibitor and inducer of neuronal differentiation; inhibits the refolding activity of the complex of Hsp60 with the co-chaperone Hsp10 in a cell-free assay (IC50 = 14.4 µM); induces differentiation of primary rat hippocampal NPCs into neurons (EC50 = ~1 µM) and inhibits BMP4-induced differentiation of primary rat hippocampal NPCs into astrocytes at 5 µM; increases nuclear localization of the Tacc3 target Arnt2 in HEK293T cells expressing the rat proteins at 5 µM; reduces tumor burden and increases survival in a PDX mouse model of giant cell glioblastoma |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | KHS101 Arnt BMP-4 GBM Hsp HSPD HEK-293T 293 Tacc |
Gene, Accession, CAS # | CAS: 1262770-73-9 |
Catalog # | 37544-50 |
Price | $507.00 |
Order / More Info | KHS-101 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |