KDU691 from CAYMAN CHEMICAL COMPANY
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| Product Name | KDU691 |
| Description | An antimalarial compound; inhibits the activity of recombinant P. vivax PI4K (IC50 = 1.5 nM); selective for P. vivax PI4K over recombinant human PI4KβIII and PI3Kα, -β, -γ, and -δ (IC50s = 7.9, 8.8, 2.4, 8, and 3.4 µM, respectively), as well as VPS34 (IC50 = >9.7 µM) and 36 additional kinases in a panel of lipid and protein kinases (IC50s = >10 µM); active against P. falciparum and P. yoelii schizonts (IC50s = 0.06 and 0.04 µM, respectively), as well as P. cynomolgi schizonts and hypnozoites (IC50s = 0.11 and 0.2 µM, respectively); completely prevents, but does not eradicate established, P. cynomolgi infection in rhesus monkeys at 20 mg/kg |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 1618681-91-6 KDU-691 Plasmodium PI-4K PI4K-βIII PI3K-α PI3Kβ PI3Kγ PI3Kδ VPS-34 anti-malarial |
| Gene, Accession, CAS # | CAS: 1513879-19-0 |
| Catalog # | 29019-1 |
| Price | $59.00 |
| Order / More Info | KDU691 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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