NMS-E973 from CAYMAN CHEMICAL COMPANY
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| Product Name | NMS-E973 |
| Description | An HSP90 inhibitor (IC50 = 10 nM in a fluorescence polarization assay); decreases HER2 protein expression (IC50 = 110 nM) in BT474 breast cancer cells; inhibits the growth of a 16 cancer cell line panel (IC50s = 13-362 nM); reduces tumor growth by 74% in an A2780 mouse xenograft model at a dose of 60 mg/kg, i.v., per day for ten days; completely eradicates MOLM-13 acute myeloid leukemia tumors in a mouse xenograft model |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | NMSE-973 NMSE973 HER-2 MOLM13 hsp-90 BT-474 AML human epidermal growth factor extracellular?signal?regulated kinase |
| Gene, Accession, CAS # | CAS: 1253584-84-7 |
| Catalog # | 22352-10 |
| Price | $257.00 |
| Order / More Info | NMS-E973 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY