E7820 from CAYMAN CHEMICAL COMPANY
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| Product Name | E7820 |
| Description | An angiogenesis inhibitor with anticancer activity; inhibits bFGF- and VEGF-stimulated HUVEC proliferation (IC50s = 0.1 and 0.081 µg/ml, respectively); inhibits bFGF- and VEGF-stimulated tube formation of HUVECs (IC50s = 0.2 and 0.24 µg/ml, respectively); selectively decreases the surface expression and mRNA levels of integrin α2 over CD31 and VE-cadherin in HUVECs; reduces tumor growth and inhibits angiogenesis in a WiDr colorectal cancer mouse xenograft model at 200 and 400 mg/kg; reduces tumor weight in a panel of seven human colon, breast, pancreas, and kidney cancer mouse xenograft models; completely inhibits tumor growth in KP-1 pancreatic and LoVo colon cancer mouse xenograft models; inhibits tumor growth in KP-1 and COLO 320DM mouse orthotopic transplantation models, |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | E-7820 ER 68203-00 ER68203 ER6820300 α-2 CD-31 KP1 320-DM anti-cancer |
| Gene, Accession, CAS # | CAS: 289483-69-8 |
| Catalog # | 25502-5 |
| Price | $37.00 |
| Order / More Info | E7820 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY