DNA/RNA Oxidative Damage (High Sensitivity) ELISA Kit from CAYMAN CHEMICAL COMPANY

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Product NameDNA/RNA Oxidative Damage (High Sensitivity) ELISA Kit
DescriptionBoth DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer. The repair processes that are initiated to correct this damage release multiple oxidized guanine species into the urine. Cayman Chemical has developed this immunoassay for the measurement of DNA/RNA oxidative damage that detects all three oxidized guanine species; 8-hydroxy-2'-deoxyguanosine from DNA, 8-hydroxyguanosine from RNA, and 8-hydroxyguanine from either DNA or RNA. Some commercial vendors offer immunoassays that detect only 8-hydroxy-2'-deoxyguanosine, and not the other two molecules. The advantage of the Cayman kit is that it captures a more complete set of biologically relevant products of oxidative damage than do assays that are restricted to analysis of only 8-hydroxy-2'-deoxyguanosine. However, because Cayman's kit recognizes more than 8-hydroxy-2'-deoxyguanosine, it is not valid to compare the results from the Cayman ELISA Kit to an LC/MS analysis of 8-hydroxy-2'-deoxyguanosine. The ELISA value will always be significantly higher than LC/MS because the ELISA also detects 8-hydroxyguanosine and 8-hydroxyguanine.
Size96 Solid
Concentrationn/a
ApplicationsELISA
Other Names8-hydroxy-2'-Deoxyguanosine|8-OH-2dG|8-OH-DG|DNA/RNA Oxidative Damage (High Sensitivity) EIA Kit
Gene, Accession, CAS #n/a
Catalog #589320-96SOLIDWELLS
Price$574.00
Order / More InfoDNA/RNA Oxidative Damage (High Sensitivity) ELISA Kit from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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