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Product Name | ICA 069673 |
Description | A Kv7 channel activator; selective for Kv7.2/7.3 over Kv7.3/7.5 (EC50s = 0.69 and 14.3 µM, respectively) and activates Kv7.4, Kv7.5, and heteromeric Kv7.4/7.5 channels in a dose-dependent manner; has no activity against hERG, Nav1.5, and Kv7.1 cardiac ion channels (IC50s = >30 µM); increases latency to first tonic-clonic seizure in the rat maximal electroshock and pentylentetrazol-induced seizure models (ED50s = 1.5 and <1 mg/kg, respectively), |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ICA069673 ICA69673 Kv 7.2 7.3 7.5 7.4 NaC |
Gene, Accession, CAS # | CAS: 582323-16-8 |
Catalog # | 22995-50 |
Price | $723.00 |
Order / More Info | ICA 069673 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |